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| domain | vihver.pt |
| summary | Here’s a summary of the website content, focusing on key themes and information: Overall Theme: The website comprehensively addresses the complex interplay between HIV infection, chronic kidney disease (CKD), neurocognitive disorders, cancer risk, and the aging process in individuals with HIV. It emphasizes the importance of tailored management strategies, particularly considering the unique challenges presented by older adults and co-infections like Hepatitis C. Key Areas Covered: * Chronic Kidney Disease (CKD) in HIV: The website details the epidemiology of CKD in HIV patients, its multifactorial origins (including tenofovir toxicity), and the bidirectional relationship with Hepatitis C. It highlights the need for careful monitoring and specific management approaches for those co-infected. * Neurocognitive Disorders (HAND): It explores the prevalence of HAND in HIV-infected individuals, risk factors, and evolving epidemiology – particularly regarding the impact of antiretroviral therapy. It discusses diagnostic evaluations, mechanistic factors, and the need for comprehensive management. * Cancer Risk: The website examines the increased risk of non-AIDS-defining cancers (NADCs) in HIV patients, including lung cancer, hepatocellular carcinoma, and gastric cancers. It investigates oncogenic viruses, age-related factors, and screening recommendations. * Aging with HIV: A significant portion is devoted to the unique challenges of aging with HIV, focusing on polypharmacy, drug interactions, pharmacokinetic changes, and the increased risk of comorbidities. It highlights the importance of individualized treatment plans and monitoring. * Treatment Considerations: The content discusses specific antiretroviral drugs, focusing on potential nephrotoxicity and the impact of interactions. Recommendations are offered for selecting appropriate medications, especially in older adults. Key drugs are referenced, including Raltegravir and Doravirine. * Clinical Research & Studies: The site includes references to numerous clinical trials and studies (STARTMRK, DRIVE-AHEAD, etc.), highlighting ongoing research and best practices. * Diagnostic & Monitoring: It emphasizes the importance of neurological evaluations, laboratory tests, and regular monitoring of renal function. Key Messages/Takeaways: * Increased Risk: HIV infection significantly increases the risk of CKD, HAND, and cancer. * Complex Interactions: Drug interactions and pharmacokinetic changes become more pronounced with aging. * Individualized Care: Management strategies must be tailored to the individual's age, comorbidities, and HIV status. * Comprehensive Monitoring: Close monitoring of renal function and neurological status is critical. * Research Driven: The field is actively evolving, with new research continuously shaping clinical practice. Abbreviations & Resources: The document uses numerous abbreviations throughout the text and includes a list of relevant studies, research projects, and resources to further exploration. |
| title | HIV ambition - HIV - HIV - HIV - HIV |
| description | HIV ambition - HIV - HIV - HIV - HIV |
| keywords | para, drug, patients, infection, interactions, risk, cancer, anos, aids, drive, management, hand, sida, defining, cancers, disorders |
| upstreams | msd.pt |
| downstreams | |
| nslookup | A 195.22.14.232 |
| created | 2024-11-30 |
| updated | 2025-10-24 |
| summarized | 2026-01-31 |
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